Rough Endoplasmic Reticulum Structure and Function | Rough ER Simplified

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this is 2 Minute Classroom and today we're talking about the rough endoplasmic reticulum

or rough ER for short

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The rough ER is a series of interconnected membranous structures

that appears studded under powerful microscopes

These studs are actually ribosomes and give this portion of the ER its rough appearance and name

It sits next to the nucleus in the cell

and is actually continuous with the outer membrane of the nucleus

the nuclear envelope

The rough ER is responsible for the synthesis and modification of proteins

You can learn more about proteins by clicking the icon in the upper right hand corner

The proteins that are modified in and passed through the rough ER

are primarily membrane bound proteins

that will function in either the cell membrane itself

or the membranes of the other organelles within the cell

Some proteins from the rough ER will be secreted out of the cell and vesicles

to perform functions throughout the body

Such as signaling between nerve cells

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